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Scientist, Protein Sciences

Company: Molecular Templates
Location: Austin
Posted on: June 14, 2019

Job Description:

Company Description:Molecular Templates (MTEM) is a clinical stage biopharmaceutical company targeting a variety of cancers through development of its innovative proprietary Engineered Toxin Body (ETB)platform. MTEM's first immunotoxin, MT-3724, is in clinical development for non-Hodgkin's lymphoma. Pipeline products for additional oncology targets are being advanced toward clinical development. For more information, please visit MTEM's website at .Position Overview:Molecular Templates is seeking a highly-skilled and highly-motivated professional to support optimization and transfer of novel protein-based therapeutics to manufacturing activities. The Scientist will be responsible for designing and implementing the manufacturing process and procedure from early-stage process development to manufacturing scale-up; developing methods for production, purification, fermentation and testing of new process formulas, technologies and products. This includes new product scale-up, process optimization, technology transfer and process validation activities, as well as developing production procedures and product specifications. This position will require excellent technical, analytical and problem-solving skills, along with ability to operate independently on progressively more complex activities and projects.Job Responsibilities will include:

  • Develop methods for fermentation, purification, production and testing of new process formulas, technologies and products, including but not limited to: new product scale-up, microbial fermentation, protein purification, process optimization, analytical characterization, technology transfer and process validation activities and early-stage development of production procedures and product specifications
  • Establish operating equipment specifications to improve manufacturing techniques
  • Maintain knowledge of scientific trends and industry processes through readings, conferences and seminars; review literature to enhance or improve manufacturing procedures and methods. Use professional concepts and company policies and procedures to solve a wide range of difficult problems in creative and practical ways
  • May participate in the development of patent applications or regulatory documentation
  • Other duties and special projects, as assigned Qualifications:
    • Master's degree in Life sciences, chemical engineering, biochemical engineering or related relevant field with three (3) years of experience; Or, PhD in Life Sciences with one (1) year of experience
    • Minimum of one (1) year of relevant industry conducting bioprocessing development, required
    • Demonstrated technical proficiency in biologic drug substance processes
    • Proven experience with protein expression, purification, formulation development and/or engineering, required
    • Demonstrated experience using bioreactor (5L/10L), such as AKTA
    • Demonstrated experience with FPLC, column chromatography, column packing, buffer exchange and use of common resins
    • Excellent written and verbal communication skills
    • Excellent computer skills
    • Excellent analytical skills and problem-solving skills
    • Excellent organizational, time management, and multi-tasking skills
    • Ability to maintain highest standards of accuracy and attention to detail
    • Ability to function independently and exercise good judgement, as well as provide thought leadership
    • Ability to identify problems and solutions then act to resolve Reporting Structure:This position currently has no supervisory responsibilities. This position reports to Sr. Manager, Protein Sciences.Molecular Templates, Inc. is an Equal Opportunity Employer and offers competitive salaries and benefits.Molecular Templates Inc

Keywords: Molecular Templates, Austin , Scientist, Protein Sciences, Other , Austin, Texas

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